ABSTRACT
Regular aerobic exercise improves the inflammatory status in different lung diseases. However, the effects of long-term aerobic exercise on the lung response have not been investigated. The present study evaluated the effect of aerobic exercise on the lung inflammatory. 12 adult male Wistar rats were divided to 2 groups: A: control [n=6], B: aerobic exercise [five times per week for 4 week; n=6]. The gene expression of NF-kappaB and TNF-alpha were analyzed in lung tissue by Real time-PCR. In order to determine the significant differences between groups independent t-test were used. Aerobic exercise inhibited the gene expression of NF-kappaB and TNF-alpha. But there was no significant difference between A and B groups for TNF-alpha and NF-kappaB. We conclude that four week aerobic exercise decrease inflammatory status in lung tissue. Our results indicate a need for human studies that evaluate the lung responses to aerobic exercise
ABSTRACT
To study the effects of Polarized Polychromatic Noncoherent Light [Bioptron] therapy on patients with carpal tunnel syndrome [CTS]. This study was designed as a randomized clinical trial. Forty four patients with mild or moderate CTS [confirmed by clinical and electrodiagnostic studies] were assigned randomly into two groups [intervention and control goups]. At the beginning of the study, both groups received wrist splinting for 8 weeks. Bioptron light was applied for the intervention group [eight sessions, for 3/weeks]. Bioptron was applied perpendicularly to the wrist from a 10 centimeters distance. Pain severity and electrodiagnostic measurements were compared from before to 8 weeks after initiating each treatment. Eight weeks after starting the treatments, the mean of pain severity based on Visual Analogue Scale [VAS] scores decreased significantly in both groups. Median Sensory Nerve Action Potential [SNAP] latency decreased significantly in both groups. However, other electrophysiological findings [median Compound Motor Action Potential [CMAP] latency and amplitude, also SNAP amplitude] did not change after the therapy in both groups. There was no meaningful difference between two groups regarding the changes in the pain severity. Bioptron with the above mentioned parameters led to therapeutic effects equal to splinting alone in patients with carpal tunnel syndrome. However, applying Bioptron with different therapeutic protocols and light parameters other than used in this study, perhaps longer duration of therapy and long term assessment may reveal different results favoring Bioptron therapy
ABSTRACT
The aim of this research was to examine the dimensions of axis I disorders during the first four months after Traumatic Brain Injury [TBI] and mental states after TBI. Overall, 238 patients [43 females and 195 males] with TBI, in a descriptive-longitudinal study, were selected by consecutive sampling procedure and each of them undergone medical examinations. After 4 months of follow-up, 65.1% [155 cases] of the patients referred to a psychiatrist to determine the nature of their mental disorder due to TBI, using a structured clinical interview, based on the Diagnostic and Statistical Manual of Mental Disorders, 4th ed. [DSM-IV] .The results showed that 75.5% [117 cases] of the patients had post-injury mental disorders secondary to TBI. Of these, 88 patients [75.2%] showed the comorbidity of mental disorders. However, the most common mental disorders due to TBI included personality change [58.6%], mood disorders [32.3%], anxiety disorders [20%], sleep disorders [19.3%], chronic amnesia [12.9%] and somatoform disorders [1.3%]. Delirium, eating and psychotic disorders due to TBI, each up to 0.64%, were also diagnosed.The high frequency of mental disorders is evident in the acute phase after TBI, along with many novel cases of personality changes, mood and anxiety disorders. Therefore TBI patients must be monitored and evaluated at least in a 4-month period after the trauma to reduce the risk of mental disorders incident.